Recombinant IL-4RA (Dupilumab Biosimilar) 抗体
This anti-IL-4RA (Dupilumab Biosimilar) antibody is a 小鼠 单克隆 antibody detecting IL-4RA (Dupilumab Biosimilar) in FACS 和 in vivo. Suitable for 人.
Quick Overview for Recombinant IL-4RA (Dupilumab Biosimilar) 抗体 (ABIN7795142)
抗原
IL-4RA (Dupilumab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This IL-4RA (Dupilumab Biosimilar) antibody is un-conjugated
应用范围
Flow Cytometry (FACS), In vivo Studies (in vivo)
质量等级
Research Grade
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Expression System
- Mammalian cells
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原理
- Dupilumab Biosimilar, Endotoxin 0.05 EU/mg
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产品特性
- What is dupilumab biosimilar research grade? Dupilumab is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis. Dupilumab binds to the alpha subunit of the interleukin-4 receptor (IL-4Ra), making it a receptor antagonist. Through blockade of IL-4Ra, dupilumab modulates signaling of both the interleukin 4 and interleukin 13 pathways. Dupilumab biosimilar uses the same protein sequences as the therapeutic antibody dupilumab.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- Less than 0.5 EU/mg of protein as determined by LAL method
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免疫原
- Human IL4R alpha
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anti-IL-4RA (Dupilumab Biosimilar) antibody
Research Grade 适用: 人 FACS, ELISA 宿主: Human Monoclonal unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- IL-4RA (Dupilumab Biosimilar)
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别名
- Dupilumab Biosimilar
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物质类
- Biosimilar
抗原
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